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Panion's epilepsy drug candidate shows positive initial results in a long-term study by CombiGene

Panion Animal Health AB develops a new epilepsy medicine for dogs based on CombiGene's drug vector CG01. Initial results from CombiGene's long-term study in rats was released yesterday in a message, which is highly relevant for Panion's development of the product for epilepsy in dogs.

Professor Merab Kokaia from Lund University, who has lead the study, expresses his joy over the results.

http://combigene.com/2/wp-content/uploads/2017/12/ CombiGene_PM_20171206_long-term_study.pdf

He explains that the study analyses three different parameters related to the epileptic brain.

  • Magnetic Resonance scanning (MR) evaluates the magnitude of damage in the brain;

  • Electro-encephalography (Video-EEG) observes the epileptic attacks and measures the electric activity of the brain during a seizure;

  • Histological analysis of the brain tissue that evaluates changes in the epileptic brain tissue compared to normal tissue and measures the expression of CG01 in the tissue. 

This film presents the study:
https://vimeo.com/245921380 (English subtitles).

"We congratulate CombiGene with the excellent performance of this important in-vivo study, which confirms our trust in the scientific robustness of the future treatment" says Anja Holm, CEO of Panion.. 

DECEMBER 7 2017

For further information, please contact:
Anja E. H. Holm, CEO | + 45-22 94 66 00
anja.holm@panion-animalhealth.com 

Developing animal health - In Panion, we want to improve the quality of life for animals suffering from chronic diseases. We are convinced that gene therapy has promising prospects. Our aim is to develop and commercialize a gene therapy treatment for dogs with drug refractory epilepsy, based on CombiGene AB's technology and platform. Panion Animal Health AB is listed at AktieTorget. 

2017-12-11

Panion Animal Health AB has received the European Medicines Agency's acceptance of the classification as MUMS (Minor Use Minor Species) for our epilepsy product for both dogs and cats. The request for classification was submitted to the Committee for Medicinal Products for Veterinary Use (CVMP) in the European Medicines Agency (EMA) earlier in 2017 and has now been successfully evaluated. 

2017-12-07

Panion Animal Health AB develops a new epilepsy medicine for dogs based on CombiGene's drug vector CG01. Initial results from CombiGene's long-term study in rats was released yesterday in a message, which is highly relevant for Panion's development of the product for epilepsy in dogs.

2017-11-24

Panion has an active status as SME (Small and Medium-sized Enterprise) - at the European Medicines Agency (EMA), which gives access to a number of benefits, information sources, and financial incentives. CEO Anja Holm attended the SME InfoDay on Friday 17 November at the EMA's offices where agency officials together with scientific and regulatory experts from the European Network presented developments and were ready to meet and discuss with companies on an informal basis.

2017-11-21

Period July-September 

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  • Operating profit: kSEK -923 (-43)
  • Earnings per share: SEK -0,25 (-0,01)
  • Liquidity at the end of the period: kSEK 1 166 (541)

Period January-Sept 

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  • Operating profit: kSEK -3 501 (-43)
  • Earnings per share: SEK -0,25 (-0,01)
  • Liquidity at the end of the period: kSEK 1 166 (541)
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